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KMID : 0352819880040010143
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Kosin Medical Journal
1988 Volume.4 No. 1 p.143 ~ p.153
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A Pathological Observation on Pancreatoblastoma in Korean
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Abstract
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A pathological observation on four cases of pancreatoblastoma in Korean, associated with a review of Korean language literature, is per-formed. By light microscopy, all cases revealed similar histological findings which support the opinion that pancreatoblastoma has a characteristic morphological features and the tumor is an independent disease entity. The four cases reveals squamoid corpuscles and organoid
architecture with a variable degree of acinic differentiation plus areas of sheets of cells which are less differentiated. Electron microscopic observations show an admixture of dark cells and light cells. In th e cells showing acinic differentiation, a large number of electron-dense membrane bound zymogen-like granules are seen in cytoplasm. At the apical border, the cells show microvilli. The cells of the squamoid corpuscles show filamentous structure and electron dense granules in cytoplasm.
A clinicopathological review of the four cases of pancreatoblastoma in Korean, with focuses on age, sex, site of neoplasm, diagnostic criteria, validity of subclassification with respect to prognosis, and significance of elevation of serum AFP etc is performed.
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KEYWORD
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